Regenerative medicine · Stromal vascular fraction
CSN Time Machine™
The miracle of SVF — an autologous stem-cell point-of-care system that safely and sterilely isolates the stromal vascular fraction from the patient’s own fat, inside a closed surgical circuit.
15,000+SVF cases worldwide
~2 hTotal procedure
15 minMini-liposuction
10–40MCells from 50 mL
Cell Surgical Network®The point-of-care system
From mini-liposuction to SVF in about two hours
The patented Time Machine™ uses two specialized syringes to isolate SVF — mesenchymal stem cells, hematopoietic stem cells, pericytes and pre-adipocytes — from unwanted fat, oil and debris, all within a closed surgical circuit.
The process is simple: a 15-minute mini-liposuction under local anesthesia, followed by isolation with a GMP-grade collagenase enzyme. Its unique design eliminates the need for laminar flow hoods or pipetting.
- Used in over 15,000 SVF cases within the Cell Surgical Network
- More than a dozen peer-reviewed publications
- One of the only closed surgical systems designed for processing stem cells in an operating room
- Can also be applied for autologous fat transfer procedures
Why SVF is powerful
A rich, abundant source of regenerative cells
Rich source
Many cell types
MSCs, hematopoietic stem cells, pericytes, preadipocytes, exosomes and growth factors.
High yield
500–2000×
More stem cells compared to bone marrow; about 10–40 million cells from just 50 mL of SVF.
Easy extraction
Minimally invasive
Fat tissue is abundant and can be harvested with minimal invasiveness compared to bone marrow.
Potency
Younger, dormant cells
Fat-derived stem cells are metabolically resting, well-preserved and highly viable.
Immunomodulation
Regulates inflammation
Superior ability to regulate inflammation and modulate the immune system.
Regeneration
Tissue repair
Promotes tissue repair, angiogenesis and faster recovery across multiple medical applications.
Viability
High survival
Cells are well-preserved and sequestered in fat, maintaining strong survival and functionality.
Autologous
Patient-derived
Harvested from the patient’s own tissue for safe, natural regeneration.
Cell characterisation
Key cellular markers of SVF
SVF contains MSCs, hematopoietic stem cells, pericytes and preadipocytes, as well as endothelial cells, immune cells, exosomes and growth factors.
- CD34+
- Hallmark of stromal and endothelial progenitor cells
- CD45−
- Excludes hematopoietic lineage, confirming regenerative purity
- CD31+/−
- Highlights the endothelial fraction for vascular repair
- CD146
- Pericyte marker supporting vessel stability
- CD73 / CD90 / CD105
- Classical MSC markers (in culture)
- SDF-1α
- Chemokine that guides stem cell homing and neovascularization
- P-selectin (CD62P)
- Platelet adhesion molecule regulating inflammation and repair
- Coefficient of variation
- Measure of reproducibility and consistency in SVF processing
Our equipment
A complete SVF workstation
Cell Surgical Network®
A global network of physicians
500+Physician networks
Across 25 U.S. states, with additional offices in China, Canada, Chile, Korea, Panama, South East Asia, South Africa, New Zealand, the Middle East, Malta, Czech Republic and Turkey.
IRBSurgical sterility
The closed system offers surgical sterility for IRB compliance and optimal patient safety. Physicians share protocols, techniques and data collection.
Bionics Medical · UAE & KSA
Bring CSN Time Machine™ SVF to your clinic.
For healthcare professionals. Product information provided by the manufacturer (Cell Surgical Network). Distributed by Bionics Medical in the UAE and Saudi Arabia.